Wound Repair Regen. 2025 May-Jun;33(3):e70043. doi: 10.1111/wrr.70043.ABSTRACTRotator cuff (RC) pathology encompasses a wide range of conditions, which include bursitis, tendinitis, tendinosis, partial thickness tears and full-thickness tears. To treat painful musculoskeletal problems, low-level las
ACS Pharmacol Transl Sci. 2025 Apr 16;8(5):1270-1281. doi: 10.1021/acsptsci.4c00552. eCollection 2025 May 9.ABSTRACTInflammatory response, oxidative stress, and pyroptosis play important roles in the pathogenesis of diabetic kidney disease (DKD), and the NOD-like receptor protein 3 (NLRP3) inflammas
Acta Pharm Sin B. 2025 Mar;15(3):1397-1414. doi: 10.1016/j.apsb.2024.12.040. Epub 2025 Jan 4.ABSTRACTThe clinical antiprotozoal drug nitazoxanide has been demonstrated to improve the experimental diabetes mellitus, lipid metabolism disorders, atherosclerosis and inhibit inflammation. Since the patho
Sci Rep. 2025 May 14;15(1):16764. doi: 10.1038/s41598-025-01757-x.ABSTRACTThe prevalence of type 2 diabetes mellitus (T2DM) has reached epidemic proportions globally, posing a significant burden on public health. Dysregulation of lipid metabolism and insulin resistance in T2DM often leads to hepatic
No abstractHeart Lung Circ. 2025 May 13:S1443-9506(25)00183-0. doi: 10.1016/j.hlc.2024.11.036. Online ahead of print.NO ABSTRACTPMID:40368670 | DOI:10.1016/j.hlc.2024.11.036
PLOS Glob Public Health. 2025 May 14;5(5):e0003816. doi: 10.1371/journal.pgph.0003816. eCollection 2025.ABSTRACTThe burden of type 2 diabetes is rapidly increasing in low- and middle-income countries (LMICs), but determinants are not well-characterized. Household air pollution (HAP) from indoor biof
Cell Rep. 2025 May 13;44(5):115691. doi: 10.1016/j.celrep.2025.115691. Online ahead of print.ABSTRACTUsing in vitro models of lipotoxicity and islets from the db/db mouse model of type 2 diabetes (T2D), we show that endoplasmic reticulum (ER) stress impairs β cell function. This is unrelated to apop
Hypertension. 2025 May 14. doi: 10.1161/HYPERTENSIONAHA.124.24472. Online ahead of print.ABSTRACTBACKGROUND: Hypertensive disorders of pregnancy (HDP) are among the most common pregnancy complications and leading causes of maternal morbidity and mortality worldwide. This study aimed to perform the l
Front Aging. 2025 Apr 29;6:1507232. doi: 10.3389/fragi.2025.1507232. eCollection 2025.ABSTRACTOBJECTIVE: The purpose of this study was to conduct a systematic review and meta-analysis to evaluate the effects of exercise on postural control, gait, and muscle strength in older adults with diabetic per
CONCLUSION: BMI, Hgb, age and Gensini score can be used to predict peak METs and BMI, Hgb and age can be used to predict O(2)P(peak) in patients with CAD clinically. Thus, tailored exercise program should be prescribed for individual CAD patient undergoing cardiac rehabilitation and modifying clinic
Intest Res. 2025 May 14. doi: 10.5217/ir.2024.00199. Online ahead of print.ABSTRACTBACKGROUND/AIMS: Patients with ulcerative colitis (UC) in remission commonly restrict thir lifestyle to prevent relapse; however, the effectiveness and impact on quality of life (QOL) is unclear. This study investigat
J Clin Med. 2025 May 1;14(9):3143. doi: 10.3390/jcm14093143.ABSTRACTIntroduction: During the COVID-19 pandemic, the availability of cardiac rehabilitation (CR) was limited. On the other hand, during that period of epidemic restrictions, patients with acute coronary syndrome (ACS) required careful co
Sensors (Basel). 2025 Apr 25;25(9):2722. doi: 10.3390/s25092722.ABSTRACTFatigability, a phenotype of poor energy regulation, is associated with lower physical activity in older adults, but independent associations with sedentary behavior are unknown. We examined whether sedentary behavior was associ
Nutrients. 2025 Apr 29;17(9):1498. doi: 10.3390/nu17091498.ABSTRACTBACKGROUND/OBJECTIVES: Metabolic syndrome (MetS) is a prevalent health condition characterized by central obesity, insulin resistance, hypertension, and dyslipidemia, increasing the risk of cardiovascular disease and type 2 diabetes.
Nutrients. 2025 Apr 27;17(9):1477. doi: 10.3390/nu17091477.ABSTRACTBackground/Objectives: Sarcopenia, abdominal obesity, and sarcopenic obesity are prevalent and clinically significant in older adults, each shaped by diverse biopsychosocial factors. However, integrative analyses using nationally rep
Nutrients. 2025 Apr 23;17(9):1411. doi: 10.3390/nu17091411.ABSTRACTBackground: Hyper-LDL-cholesterolemia is a key contributor to cardiovascular diseases (CVDs), and both genetic predisposition and lifestyle influence it. This study aimed to develop personalized strategies for managing hyper-LDL-chol
Nutrients. 2025 Apr 22;17(9):1404. doi: 10.3390/nu17091404.ABSTRACTBackground/Objectives: High-intensity interval training (HIIT) and time-restricted feeding (TRF) have shown potential in enhancing glucose metabolism, increasing insulin sensitivity, and promoting muscle health. This study investigat
Int J Mol Sci. 2025 Apr 28;26(9):4199. doi: 10.3390/ijms26094199.ABSTRACTInsulin resistance is more common in the elderly, and with the improvement in people's living standards and changes in lifestyle habits, the incidence of insulin resistance in other age groups is also increasing year by year. O
Healthcare (Basel). 2025 Apr 28;13(9):1012. doi: 10.3390/healthcare13091012.ABSTRACTBackground/Objectives: Older adults with type 2 diabetes mellitus (T2DM) often experience impaired physical function and metabolic control. This study aimed to evaluate the effectiveness of a 12-week Pilates-based in
Nat Metab. 2025 May 13. doi: 10.1038/s42255-025-01296-9. Online ahead of print.ABSTRACTAdipose tissue (AT) is a complex connective tissue with a high relative proportion of adipocytes, which are specialized cells with the ability to store lipids in large droplets. AT is found in multiple discrete de
Gerontology. 2025 Apr 15:1-23. doi: 10.1159/000545848. Online ahead of print.ABSTRACTReductions in oxygen availability at altitude reduce oxygen supply to the myocardium. This reduction in oxygen supply may be problematic for patients with cardiovascular disease and/or associated comorbidities such
J Clin Endocrinol Metab. 2025 May 13:dgaf285. doi: 10.1210/clinem/dgaf285. Online ahead of print.ABSTRACTCONTEXT: Insulin Resistance (IR) contributes to the pathogenesis of type 2 diabetes mellitus (T2DM) and is a risk factor for cardiovascular and neurodegenerative diseases. Amino acid and lipid me
Indian J Dermatol Venereol Leprol. 2025 Mar 4:1-11. doi: 10.25259/IJDVL_1094_2024. Online ahead of print.ABSTRACTThe gut microbiome and human body have co-evolved in a synergistic host-microbial relationship. The ideal composition of human gut microbiota is an elusive concept, but every individual h
Circulation. 2025 May 13. doi: 10.1161/CIRCULATIONAHA.124.070279. Online ahead of print.ABSTRACTBACKGROUND: Exercise improves functional outcomes in patients with diabetic cardiomyopathy (DiaCM). The molecular mechanism underlying cardiac benefits of exercise in DiaCM remains incompletely understood
