Cureus. 2025 Apr 14;17(4):e82258. doi: 10.7759/cureus.82258. eCollection 2025 Apr.
ABSTRACT
Treatment of liver abscesses in patients with transfusion-dependent thalassaemia remains a challenging task due to the interplay of multiple factors, including difficult venous access and the co-existence of other organ dysfunction, such as diabetes mellitus. We report case histories of three transfusion-dependent thalassaemia patients with liver abscesses, two of whom had repeated episodes of the disease. We recommend a prolonged regimen of intravenous and oral antibiotics to eliminate the infection, along with more vigilant and regular follow-up using imaging for early detection of recurrence. Finally, we highlight the importance of maintaining continuous venous access - another often overlooked challenge among thalassaemia patients.
PMID:40370878 | PMC:PMC12077915 | DOI:10.7759/cureus.82258