J Clin Med. 2025 May 7;14(9):3232. doi: 10.3390/jcm14093232.ABSTRACTPurpose: The success of solid organ transplantation and the consequent increase in the patients on the waiting list has led to an increased utilization of donor kidneys with a high kidney donor profile index (KDPI)/expanded criteria
J Clin Med. 2025 May 6;14(9):3230. doi: 10.3390/jcm14093230.ABSTRACTObjectives: This study compared the efficacy of continuous insulin infusion therapy (CIT) versus standard bolus insulin therapy in maintaining optimal perioperative glycemic control in patients with type 2 diabetes mellitus (T2DM) u
J Clin Med. 2025 May 6;14(9):3222. doi: 10.3390/jcm14093222.ABSTRACTBackground/Objectives: Mini-dose glucagon (MDG) is a safe and effective option for managing hypoglycemia during prolonged, repetitive fasts in people with type 1 diabetes (pwT1D) during Ramadan. We aimed in this study to evaluate th
J Clin Med. 2025 May 6;14(9):3213. doi: 10.3390/jcm14093213.ABSTRACTType 2 diabetes (T2D) is the leading cause of chronic kidney disease (CKD) and is a risk factor for progression to end-stage kidney disease and cardiovascular morbidity and mortality. Despite pharmacologic treatment, residual risk o
J Clin Med. 2025 May 6;14(9):3215. doi: 10.3390/jcm14093215.ABSTRACTIntroduction: Hyperinsulinemia and insulin resistance are strong predictors of cardiometabolic diseases, which disproportionately affect individuals across gender, racial/ethnic, and socioeconomic groups. We aim to estimate and test
J Clin Med. 2025 May 4;14(9):3182. doi: 10.3390/jcm14093182.ABSTRACTObjective: The use of transcatheter aortic valve implantation (TAVI) has expanded in patients with severe aortic stenosis who are deemed inoperable. However, sarcopenia may be a determining factor in their survival. The aim of our s
J Clin Med. 2025 May 4;14(9):3177. doi: 10.3390/jcm14093177.ABSTRACTBackground: Hypertension is one of the most common cardiovascular risk factors worldwide. Additionally, epidemiological studies show a worryingly high prevalence of treatment-resistant hypertension. Especially concerning is the freq
J Clin Med. 2025 May 2;14(9):3162. doi: 10.3390/jcm14093162.ABSTRACTBackground and Objectives: As the population ages, the number of hip fractures is expected to increase. Developing prevention policies requires knowledge of the factors that lead to the incidence of hip fractures. In this study, we
J Clin Med. 2025 May 2;14(9):3155. doi: 10.3390/jcm14093155.ABSTRACTBackground/Objectives: Type 2 diabetes mellitus (DM2) is characterized by the development of micro/macro-vascular complications over time. Factors influencing their course may present specific features in the primary care context. T
J Clin Med. 2025 May 1;14(9):3143. doi: 10.3390/jcm14093143.ABSTRACTIntroduction: During the COVID-19 pandemic, the availability of cardiac rehabilitation (CR) was limited. On the other hand, during that period of epidemic restrictions, patients with acute coronary syndrome (ACS) required careful co
J Clin Med. 2025 Apr 30;14(9):3123. doi: 10.3390/jcm14093123.ABSTRACTBackground/Objectives: Patients with coronary artery disease undergoing coronary artery bypass grafting (CABG) have a high prevalence of type 2 diabetes mellitus (T2DM) and prediabetes. Glucose metabolism disorders (GMDs) are often
J Clin Med. 2025 Apr 30;14(9):3121. doi: 10.3390/jcm14093121.ABSTRACTPre-eclampsia is a severe pregnancy complication affecting 5-8% of pregnancies worldwide, marked by high blood pressure and organ damage typically occurring after 20 weeks of gestation. It is a leading cause of maternal and fetal m
J Clin Med. 2025 Apr 30;14(9):3122. doi: 10.3390/jcm14093122.ABSTRACTGlucagon-like peptide-1 Receptor Agonists (GLP-1 RAs) have been one of the most discussed issues in medicine for the past few years. Initially dedicated to patients with type 2 diabetes mellitus (T2DM), the medicine turned out to b
J Clin Med. 2025 Apr 30;14(9):3103. doi: 10.3390/jcm14093103.ABSTRACTBackground/Objectives: The aim of this study was to qualitatively and quantitatively assess the bacterial domain of the gut microbiome in elderly patients with type 2 diabetes (T2D), with a focus on sex differences, glycemic contro
J Clin Med. 2025 Apr 30;14(9):3106. doi: 10.3390/jcm14093106.ABSTRACTBackground: In recent years, various authors have suggested a potential association between oral lichen planus (OLP) and thyroid disease (TD), although other studies have failed to confirm a significant relationship. The available
J Clin Med. 2025 Apr 29;14(9):3089. doi: 10.3390/jcm14093089.ABSTRACTObjective: The objective of this study was to calculate the epidemiological impact of metabolic dysfunction associated with fatty liver disease (MAFLD) and hepatic fibrosis in primary care (PC). Secondarily, we assessed the correla
J Clin Med. 2025 Apr 29;14(9):3083. doi: 10.3390/jcm14093083.ABSTRACTCardiovascular diseases and cancer are the two primary causes of mortality worldwide. Although traditionally regarded as distinct pathologies, they share numerous pathophysiological mechanisms and risk factors, including chronic in
J Clin Med. 2025 Apr 29;14(9):3065. doi: 10.3390/jcm14093065.ABSTRACTGestational diabetes mellitus (GDM) leads to increased lifelong cardiometabolic risk in both mothers and their offspring. The identification of effective strategies to contain the future risk of type 2 diabetes (T2D) and cardiovasc
J Clin Med. 2025 Apr 28;14(9):3039. doi: 10.3390/jcm14093039.ABSTRACTBackground: Anterior cervical discectomy and fusion (ACDF) is a common treatment for cervical radiculopathy and myelopathy. While generally effective, diabetes mellitus may increase postoperative complications and healthcare costs.
J Clin Med. 2025 Apr 26;14(9):3007. doi: 10.3390/jcm14093007.ABSTRACTBackground: Models of second-phase cardiac rehabilitation (CR) following myocardial infarction (MI) differ across countries. The aim of this study was to compare outcomes in MI survivors participating in outpatient and inpatient CR
J Clin Med. 2025 Apr 26;14(9):2993. doi: 10.3390/jcm14092993.ABSTRACTBackground/Objectives: Patients with periodontitis have been found to have higher salivary concentrations of malondialdehyde, a biomarker of lipid hyperoxidation, compared to healthy subjects. However, the association between saliv
J Clin Med. 2025 Apr 25;14(9):2972. doi: 10.3390/jcm14092972.ABSTRACTBackground/Objectives: Diabetes is a chronic metabolic disease affecting over 500 million adults worldwide, which is over 10% of the world's population. Diabetes is associated with a high risk of complications, including cognitive
J Clin Med. 2025 Apr 25;14(9):2967. doi: 10.3390/jcm14092967.ABSTRACTObjective: To evaluate the outcomes of a preliminary single-center experience with Robotic Roux-en-Y Gastric Bypass (R-RYGB) using the Hugo™ Robotic-assisted Surgery system, focusing on operative time, perioperative complications,
J Clin Med. 2025 Apr 25;14(9):2963. doi: 10.3390/jcm14092963.ABSTRACTBackground: The triglyceride-glucose (TyG) index has emerged as a novel surrogate marker of insulin resistance, but its changes after hepatitis C virus (HCV) eradication remain unclear. This study aimed to evaluate changes in the T
