J Diabetes Res. 2025 Apr 28;2025:5519447. doi: 10.1155/jdr/5519447. eCollection 2025.ABSTRACTA disintegrin and metalloproteinase Domain 9 (ADAM9) is a zinc-dependent proteinase involved in various biological processes. However, its role in the pathophysiology of metabolic syndrome remains unclear, a
J Diabetes Res. 2025 Apr 29;2025:9919456. doi: 10.1155/jdr/9919456. eCollection 2025.ABSTRACTBackground: Diabetes mellitus (DM) is a common chronic endocrine and metabolic disease, and its complications can involve multiple organs and seriously threaten human health. Double-stranded DNA (dsDNA) play
J Diabetes Res. 2025 Apr 25;2025:4321423. doi: 10.1155/jdr/4321423. eCollection 2025.ABSTRACTIntroduction: Ramadan fasting claims a necessary role in the management of diabetes. Many people with Type 2 diabetes insist on fasting during the holy month of Ramadan, which represents a challenge to their
J Diabetes Res. 2025 Apr 24;2025:6591307. doi: 10.1155/jdr/6591307. eCollection 2025.ABSTRACTBackground: American Indians (AIs) endure the most severe health inequities in the nation, including disproportionately high rates of Type 2 diabetes (T2D). We describe baseline characteristics for AI partic
J Diabetes Res. 2025 Apr 22;2025:5540276. doi: 10.1155/jdr/5540276. eCollection 2025.ABSTRACTAims: This study evaluates the incidence of (pre)diabetes in an Austrian population over a broad age span and addresses whether alterations in lifestyle, blood markers, and body composition are associated wi
J Diabetes Res. 2025 Apr 22;2025:3733178. doi: 10.1155/jdr/3733178. eCollection 2025.ABSTRACTAims: The study is aimed at assessing gender bias in Phase III clinical trials (CTs) of sodium-glucose cotransporter type 2 (iSGLT2) inhibitors in adults with Type 2 diabetes mellitus (T2DM). Methods: We sea
J Diabetes Res. 2025 Apr 21;2025:3800292. doi: 10.1155/jdr/3800292. eCollection 2025.ABSTRACTPurpose: The Spontaneously Diabetic Torii (SDT) fatty rat is an animal model of obese Type 2 diabetes. We previously reported that the SDT fatty rats develop diabetic cataracts. This study aimed to elucidate
J Diabetes Res. 2025 Apr 17;2025:6620727. doi: 10.1155/jdr/6620727. eCollection 2025.ABSTRACTAim: This study is aimed at assesing the impact of neuropathy on well-being and health-related quality of life (HRQoL) in adolescents with Type 1 diabetes (T1D). Methods: In a cross-sectional study, 60 adole
J Diabetes Res. 2025 Apr 16;2025:8029913. doi: 10.1155/jdr/8029913. eCollection 2025.ABSTRACTPurpose: Diabetes has been associated with an excess risk of cognitive impairment. The hyperphosphorylation of tau protein leads to neurodegeneration and is closely related to Type 2 diabetes (T2D). This stu
J Diabetes Res. 2025 Apr 15;2025:9141564. doi: 10.1155/jdr/9141564. eCollection 2025.ABSTRACTBackground: Fixed-ratio combinations (FRCs) provide an alternative to intensified conservative insulin treatments (ICTs); however, therapy simplification in patients with high total daily insulin dose (TDD)
J Diabetes Res. 2025 Apr 14;2025:2795127. doi: 10.1155/jdr/2795127. eCollection 2025.ABSTRACTBackground: Fat accumulation in the pancreas, known as nonalcoholic fatty pancreatic disease (NAFPD), is associated with obesity and may lead to prediabetes and Type 2 diabetes. Reducing endoplasmic reticulu
J Diabetes Res. 2025 Apr 12;2025:4586856. doi: 10.1155/jdr/4586856. eCollection 2025.ABSTRACTBackground: Although prediabetes increases the risk of developing diabetes, its role in neuropathy remains unclear. We aim to assess alterations in the corneal nerve structure and function in prediabetes and
J Diabetes Res. 2025 Apr 9;2025:8860118. doi: 10.1155/jdr/8860118. eCollection 2025.ABSTRACTBackground and Aims: The age-at-onset is of great importance in the heterogeneity of Type 1 diabetes mellitus (T1DM). This study was designed to define clinical and laboratory differences between child-adoles
J Diabetes Res. 2025 Mar 10;2025:9917071. doi: 10.1155/jdr/9917071. eCollection 2025.ABSTRACTEpidemiological studies proposed a bidirectional link between psoriasis (Ps) and diabetes mellitus (DM); their causal relationship remains inadequately explored. We obtained summary statistics of genome-wide
J Diabetes Res. 2025 Feb 28;2025:3661739. doi: 10.1155/jdr/3661739. eCollection 2025.ABSTRACTBackground: It remains unclear whether cholesterol-lowering therapy can reduce the incidence of microvascular complications in patients with diabetes. We aim to explore the potential causal relationship betw
J Diabetes Res. 2025 Feb 26;2025:9356676. doi: 10.1155/jdr/9356676. eCollection 2025.ABSTRACTBackground and Objective: Type 2 diabetes mellitus (T2DM) is the result of both genetic and environmental factors. Environmental factors may contribute to the occurrence and development of T2DM by influencin
J Diabetes Res. 2025 Mar 4;2025:3494697. doi: 10.1155/jdr/3494697. eCollection 2025.ABSTRACTIntroduction: Gestational diabetes mellitus (GDM) is a major health concern during pregnancy, affecting both the mother and the baby. Immune system alterations, particularly changes in lymphocyte subsets and
J Diabetes Res. 2025 Mar 8;2025:7466757. doi: 10.1155/jdr/7466757. eCollection 2025.ABSTRACTAim: To investigate the joint effects of physical activity (PA) and body mass index (BMI) on prevalent diabetes mellitus in a nationally representative sample of US adults. Materials and Methods: Data were po
J Diabetes Res. 2025 Mar 1;2025:4422330. doi: 10.1155/jdr/4422330. eCollection 2025.ABSTRACTBackground: Face-to-face diabetic interventions (FFIs) are the gold standard for diabetic care, and smartphone application (app)-based self-management interventions (SBIs) can be a potential alternative. A fe
J Diabetes Res. 2025 Mar 29;2025:4744194. doi: 10.1155/jdr/4744194. eCollection 2025.ABSTRACTAims: A lower limb ulcer is a serious complication of diabetes. The association between glycated hemoglobin (HbA1c) and lower limb ulcers needs further clarification. We aimed to comprehensively evaluate the
J Diabetes Res. 2025 Mar 28;2025:6992121. doi: 10.1155/jdr/6992121. eCollection 2025.ABSTRACTBackground: This study investigates the impact of Type 2 diabetes mellitus (T2DM) and depressive symptoms on the health-related quality of life (HRQoL) among patients at the Agricultural General Hospital in
J Diabetes Res. 2025 Mar 24;2025:2640702. doi: 10.1155/jdr/2640702. eCollection 2025.ABSTRACTBackground: This community-based randomised controlled study was aimed at evaluating a health literacy (HL) and diabetes self-management education (DSME) improvement program (HL-DSME program) among people wi
J Diabetes Res. 2025 Mar 18;2025:9966933. doi: 10.1155/jdr/9966933. eCollection 2025.ABSTRACTIntroduction: Type 2 diabetes mellitus poses global health challenges due to insulin resistance and hyperglycaemia. Understanding demographic characteristics and lipid profiles among diabetic patients is cru
J Diabetes Res. 2025 Mar 18;2025:3248350. doi: 10.1155/jdr/3248350. eCollection 2025.ABSTRACTDiabetes is a systemic metabolic disorder primarily caused by insulin deficiency and insulin resistance, leading to chronic hyperglycemia. Prolonged diabetes can result in metabolic damage to multiple organs
