Hongbo Yang il 09/05/2025

Diet, Gut Microbiota, and Histidine Metabolism Toward Imidazole Propionate Production in Relation to Type 2 Diabetes

Diabetes Care. 2025 May 9:dc242816. doi: 10.2337/dc24-2816. Online ahead of print.ABSTRACTOBJECTIVE: To examine associations of serum imidazole propionate (ImP), histidine, and their ratio with incident type 2 diabetes (T2D) and related dietary and gut microbial factors in U.S. Hispanic/Latino peopl

Vanita R Aroda il 25/04/2025

High-Dose Semaglutide (Up to 16 mg) in People With Type 2 Diabetes and Overweight or Obesity: A Randomized, Placebo-Controlled, Phase 2 Trial

Diabetes Care. 2025 Apr 25:dc242425. doi: 10.2337/dc24-2425. Online ahead of print.ABSTRACTOBJECTIVE: Studies have demonstrated dose-dependent efficacy of glucagon-like peptide 1 receptor agonists for glycemic control and body weight. The aim of this trial was to characterize the dose-dependent effe

Sebastian Linde il 24/04/2025

Historic Residential Redlining and Diabetes: Mediating Pathways and Policy Solutions

No abstractDiabetes Care. 2025 May 1;48(5):685-687. doi: 10.2337/dci25-0017.NO ABSTRACTPMID:40273354 | PMC:PMC12034890 | DOI:10.2337/dci25-0017

Zhongyu Li il 24/04/2025

Leveraging Historical Patient Data to Identify Undiagnosed Diabetes and Prediabetes in Routine Care

No abstractDiabetes Care. 2025 May 1;48(5):682-684. doi: 10.2337/dci25-0011.NO ABSTRACTPMID:40273352 | DOI:10.2337/dci25-0011

Kansak Boonpattharatthiti il 24/04/2025

Comparison of Insulin Titration Strategies for Glycemic Control in Type 2 Diabetes: A Systematic Review and Network Meta-analysis

Diabetes Care. 2025 May 1;48(5):837-845. doi: 10.2337/dc24-2661.ABSTRACTBACKGROUND: Adjusting basal insulin doses is essential for lowering blood glucose while minimizing the risk of hypoglycemia. Despite various basal insulin titration strategies being available, their comparative effectiveness rem

Antoine Christiaens il 24/04/2025

Response to Comment on Christiaens et al. Diabetes Overtreatment and Hypoglycemia in Older Patients With Type 2 Diabetes on Insulin Therapy: Insights From the HYPOAGE Cohort Study. Diabetes Care 2025;48:61-66

No abstractDiabetes Care. 2025 May 1;48(5):e79-e80. doi: 10.2337/dc25-0418.NO ABSTRACTPMID:40273348 | DOI:10.2337/dc25-0418

Ching-Yang Cheng il 24/04/2025

Comment on Christiaens et al. Diabetes Overtreatment and Hypoglycemia in Older Patients With Type 2 Diabetes on Insulin Therapy: Insights From the HYPOAGE Cohort Study. Diabetes Care 2025;48:61-66

No abstractDiabetes Care. 2025 May 1;48(5):e77-e78. doi: 10.2337/dc25-0071.NO ABSTRACTPMID:40273347 | DOI:10.2337/dc25-0071

Laura M Jacobsen il 24/04/2025

Type 1 Diabetes TrialNet: Leading the Charge in Disease Prediction, Prevention, and Immunotherapeutic Mechanistic Understanding

Diabetes Care. 2025 Apr 24:dc242908. doi: 10.2337/dc24-2908. Online ahead of print.ABSTRACTEstablished by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) in 2001, Type 1 Diabetes TrialNet (TrialNet) is an international consortium of clinical research centers that studies

Kristen J Nadeau il 24/04/2025

Youth-Onset Type 2 Diabetes: What We've Learned From Key Youth-Onset Type 2 Diabetes Studies, What We Still Don't Know, and Why It Is Important

Diabetes Care. 2025 Apr 24:dc250001. doi: 10.2337/dc25-0001. Online ahead of print.ABSTRACTIn this review, we describe the epidemiology, pathophysiology, pediatric-specific treatment response data, morbidity, and mortality of youth-onset type 2 diabetes. In recognition of the National Institute of D

Jill P Crandall il 24/04/2025

The Diabetes Prevention Program and Its Outcomes Study: NIDDK's Journey Into the Prevention of Type 2 Diabetes and Its Public Health Impact

Diabetes Care. 2025 Apr 24:dc250014. doi: 10.2337/dc25-0014. Online ahead of print.ABSTRACTThe current-day epidemic of type 2 diabetes, largely driven by increased adiposity and reduced physical activity in the setting of genetic susceptibility, is a major public health challenge. The National Insti

William T Cefalu il 24/04/2025

NIDDK: Celebrating 75 Years of Advancing Diabetes Research

No abstractDiabetes Care. 2025 Apr 24:dci250044. doi: 10.2337/dci25-0044. Online ahead of print.NO ABSTRACTPMID:40272276 | DOI:10.2337/dci25-0044

Marian Rewers il 24/04/2025

Unfolding the Mystery of Autoimmunity: The Environmental Determinants of Diabetes in the Young (TEDDY) Study

Diabetes Care. 2025 Apr 24:dc242886. doi: 10.2337/dc24-2886. Online ahead of print.ABSTRACTIn 2025, the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) at the National Institutes of Health celebrates 75 years of leadership in diabetes research. The NIDDK serves people of the

Barbara H Braffett il 24/04/2025

The NIDDK Takes on the Complications of Type 1 Diabetes: The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study

Diabetes Care. 2025 Apr 24:dc242885. doi: 10.2337/dc24-2885. Online ahead of print.ABSTRACTIn the Diabetes Control and Complications Trial (DCCT) (1983-1993), intensive therapy aimed at near-normal glycemia was compared with conventional therapy in 1,441 adolescent and adult participants with type 1

Priya Bapat il 23/04/2025

Capillary Ketone Level and Future Ketoacidosis Risk in Patients With Type 1 Diabetes Using Sodium-Glucose Cotransporter Inhibitors

Diabetes Care. 2025 Apr 23:dc250125. doi: 10.2337/dc25-0125. Online ahead of print.ABSTRACTOBJECTIVE: We aimed to determine if routine capillary blood ketone testing on well days predicts future diabetic ketoacidosis (DKA) in type 1 diabetes (T1D) using sodium-glucose cotransporter inhibitors (SGLTi

Deborah J Wexler il 23/04/2025

Weight Gain Was Associated With Worsening Glycemia and Cardiovascular and Kidney Outcomes in Patients With Type 2 Diabetes Independent of Diabetes Medication in the GRADE Randomized Controlled Trial

Diabetes Care. 2025 Apr 23:dc242825. doi: 10.2337/dc24-2825. Online ahead of print.ABSTRACTOBJECTIVE: Weight gain with glucose-lowering medications may interfere with effective type 2 diabetes (T2D) management. We evaluated weight change and the effect of weight gain on outcomes over 5 years on four

Justin B Echouffo-Tcheugui il 23/04/2025

Is the Current Lifestyle Modification Approach to Diabetes Prevention in the U.S. a Success?

Diabetes Care. 2025 Apr 23:dci240040. doi: 10.2337/dci24-0040. Online ahead of print.ABSTRACTPrediabetes is an intermediate stage between normal glycemia and diabetes and is highly prevalent, especially in adults, but is also increasingly common in young individuals. Randomized clinical trials have

Amber M Luckett il 23/04/2025

Standardized Measurement of Type 1 Diabetes Polygenic Risk Across Multiancestry Population Cohorts

No abstractDiabetes Care. 2025 Apr 23:dc250142. doi: 10.2337/dc25-0142. Online ahead of print.NO ABSTRACTPMID:40267362 | DOI:10.2337/dc25-0142

Xiaoxiao Wen il 23/04/2025

Lipidomic Markers of Processed Meat and Unprocessed Red Meat Intake and Risk of Diabetes in American Indians

Diabetes Care. 2025 Apr 23:dc242828. doi: 10.2337/dc24-2828. Online ahead of print.ABSTRACTOBJECTIVE: To identify lipidomic markers of habitual unprocessed red meat and processed meat intake and evaluate their associations with diabetes risk in American Indians.RESEARCH DESIGN AND METHODS: We studie

Stine Smedegaard il 22/04/2025

Premeal Whey Protein Lowers Postprandial Blood Glucose in Women With Gestational Diabetes Mellitus: A Randomized, Crossover Clinical Trial

Diabetes Care. 2025 Apr 22:dc242831. doi: 10.2337/dc24-2831. Online ahead of print.ABSTRACTOBJECTIVE: To examine how whey protein served as a premeal affects postprandial glucose excursions in women with gestational diabetes mellitus (GDM).RESEARCH DESIGN AND METHODS: A placebo-controlled, single-bl

John B Buse il 18/04/2025

Prevalence of Hypercortisolism in Difficult-to-Control Type 2 Diabetes

Diabetes Care. 2025 Apr 18:dc242841. doi: 10.2337/dc24-2841. Online ahead of print.ABSTRACTOBJECTIVE: Despite the use of multiple glucose-lowering medications, glycemic targets are not met in a significant fraction of people with type 2 diabetes. In this prospective, observational study we assessed

Sarah Dib il 17/04/2025

Energy Restriction, Weight Loss, Glycemia, and Breastfeeding Outcomes in Gestational Diabetes: A DiGest Trial Secondary Analysis

Diabetes Care. 2025 Apr 17:dc242625. doi: 10.2337/dc24-2625. Online ahead of print.ABSTRACTOBJECTIVE: We aimed to assess whether energy restriction, weight loss, or maternal glycemia in late pregnancy were associated with breastfeeding outcomes.RESEARCH DESIGN AND METHODS: This is a secondary analys

Quentin Perrier il 17/04/2025

Impact of Islet Transplantation on Diabetes Complications and Mortality in Patients Living With Type 1 Diabetes

Diabetes Care. 2025 Apr 17:dc250059. doi: 10.2337/dc25-0059. Online ahead of print.ABSTRACTOBJECTIVE: This study aimed to evaluate the impact of islet transplantation (IT) on diabetes complications, death, and cancer incidence.RESEARCH DESIGN AND METHODS: This retrospective, multicenter, cohort stud

Fabio Grunspun Pitta il 15/04/2025

Empagliflozin in Patients With Type 2 Diabetes Undergoing On-Pump CABG: The POST-CABGDM Randomized Clinical Trial

Diabetes Care. 2025 Apr 15:dc242807. doi: 10.2337/dc24-2807. Online ahead of print.ABSTRACTOBJECTIVE: To evaluate the efficacy and safety of empagliflozin in patients with type 2 diabetes mellitus (T2DM) undergoing elective on-pump coronary artery bypass grafting (CABG).RESEARCH DESIGN AND METHODS:

Gila Ginzburg il 15/04/2025

Islet Autoantibodies and Their Association With beta-Cell Function and Diabetes Measures in Children With Acute Recurrent and Chronic Pancreatitis

Diabetes Care. 2025 Apr 15:dc242672. doi: 10.2337/dc24-2672. Online ahead of print.ABSTRACTOBJECTIVE: In children with acute recurrent pancreatitis (ARP) and chronic pancreatitis (CP), circulating islet autoantibodies (auto-Ab) may influence β-cell function. This study reports Ab prevalence in youth